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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2b6dd0757351ede119508c15127849f77ce7a6dd91f64f65c4aa0815561f2e84' 
  AND token = 'kJN6PPJ5FtzS1TI/RXfy9cEO8mZJ9pkQnrBbwgntkJA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}