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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '054f7abad09ad8886f806a25e8beec75b7c5a75bcd0b0b84d7a735950a9f78bc' 
  AND token = 'WFZ1rCs0tfXoOD8HXPQOOBdqcPIup9h2C00COEzf/sg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}