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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4050dee6ba77d4a2e05a774eb453aebe49ffbc93b6d3bdeb38e0127b695ff956' 
  AND token = 'BQ3CNVEr/9RFYs+N1LdJqt5AwBqoug8sp8tKvkNfQd8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}