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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'fde2403afb15644e6133a7133ed4f0b54b361ee5bacb553bc3777f8c1f79d804' 
  AND token = 'mQ3bTBGxCot0dDAueOtdw/TKARSXK6zQWlt2rOdCn/0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}