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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '868e67121df0c7f873ad8b284ef1fa0dde1d6108d82dc7e9fbf6ff609ea73f72' 
  AND token = 'cmKTIdPkPWlfr/WKe+v/vvpEnCp1zd2qQJT2UmQdVnQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}