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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8de0c78aa4e79bba898d32e7fa7082db44b72632749512ea559d0f2216c64547' 
  AND token = 'pPRMougTy+F3CfHMow4uPenNFUwyX42R7VIiOy37ut4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00039

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}