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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '53e7bb8cf212792f57a0d84d23e3b6fa67a4a672dd022b5f86b4107309762291' 
  AND token = 'bwaX1QGxpKdmLddzu5Fq4iah/idPdRwM+d91d0pv3l0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}