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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '406828f490b881f8df5e5e87789e0eab51b55874726c1565a2c6e81d779887ae' 
  AND token = 'v23dJDV+GTJPWX8IMMmpBmLwdikLP47jy4RXYiYtglg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}