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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '42d196cb49763dd7abdf264ebf71a0734cda9269cd2ff76dafce470084a35c06' 
  AND token = '89Bszcf2tZC+XRrRxuA0faI4Vs/B2q9GV47lM/4Yqxs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}