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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '72cc17bd0d3acbdf39ac0b0dfb960b0e75d5f202cad3b1230fa56f51fe0a24b0' 
  AND token = 'mZu7z1ivj43HY1mX25XHKbYFJZ/5X9YR9IGwOaUW0po=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}