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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '205922881d6526888e3b38f0db6003c024514993650c8050e1b13189d393bb64' 
  AND token = 'oTp10WfUxfMpsWEbwLIAdxtbuqtEJQesmsdRZG+8zVQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}