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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b0487f8326c23e467691513354bddf929b6b34653e7a34faac29a4fd9145294e' 
  AND token = 'HG/A2AA1wenzxS4XPKCKEkNAgFM0jShHk5kBMUofYG0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}