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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'dc50d253d1d3cce90e94862cffb430cdc9a271f9adacb1cd5ef2984d0088afbc' 
  AND token = 'LIeuJ75VTPZCuuR+mcIf2DpN3RxRbtYvkGmmFIBiGQQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00015

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}