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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '11e02dd9239f7a7a59240cd3068f622dffe5255e27372966a7a9043a106de6d8' 
  AND token = 'CUot7+g2JQdEBdK1qpd0NwDCI/IZLptfKkGSG0YZ2Ps=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}