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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2354a89c055d2fd3765ec3b88a38482a4e22c0159654d55a92bce8f3307a98a4' 
  AND token = '20rB6Rdw7CbOfO0Nfk+Fg4uhitSAyQNcvE3ktPmJ/k8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}