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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '06ac93d955ac3cd057e40c2b1c1e243719a3c7f860d7c50f8dea268910c8188f' 
  AND token = 'E1rYx4P26Sdm8+z6tr202hs+xUwgndRh02V9lQ9ZcC4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}