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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a046f47062b93f33f36014b44eecb9dc7b0ab124e3db27acc7d05b51c4b7bd0f' 
  AND token = 'T5Dx8KFgAqijxuz3HnbUb9T0PK4e4iE8XanBv0v0FJk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}