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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '072a99a3bd2eb72572b02eeda67ea6ccf90d62833c15d3a0354da34af15d0ca1' 
  AND token = '8zk/AvB8fZRDphc0N8PW9A1eIzGaZOjfmAEsmM420b4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00029

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}