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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0e8b8f6090a099101b0e8368c0db5bdb50d00baf351fda70059d5cb99c3676e4' 
  AND token = 'NjHSq/v2Z3tFRskLd0mXOCkFAgrAjvaruZDwWiWDb7U=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}