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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6c8ad86ef29cd6c09f0e553cbbefd67e10f3911332bd4a95c653048976580087' 
  AND token = 'g41usIoAKkaTmoXS+LAG0t/OVU6GWl0M64MoY4XC/Z8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}