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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2f0ebb8aad6f4b5788edb04edc267f8f13c70eff31bf363a68d05f628041efdd' 
  AND token = 'sQMFwWapCRSYc894gMdY1EDUOvxFdmLpPkdS5ug6HdE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}