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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c38a0554d70c09c6bc307b24d5bfe53401fea74586787dd1aa35cd035d480ec9' 
  AND token = 'zT4Fnn4rW3jA1EqhIqgn0kFuHrheZw/nC5eWuVh4vzU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00015

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}