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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a4b4185118e900df9e8c2a474592a7a86c12898283049b1e5d1aafaf6d31d29a' 
  AND token = 'MArJQ+oAF+5E1NyF7O6ri5wcXCZiirkKYrrdkAfkEIE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}