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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '7d8cd537bf8bb53c107aace3227996ca760af927873ab9770582387c5e835a7e' 
  AND token = 'kaZ6oVatByK7x7VEtcaaNyZWF2F+fb3MHXrPRI/RJEE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}