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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd0e15f8f7096517f17ecdd4ac1db03aaab93678d293b577fb1f8a88e570fe263' 
  AND token = 'NhACFkZh10stfVM93sevmK2B8G6dE4xs+4+rvXRCDHI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}