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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2d4c489914514a0782f10e35ccf318401d29d1405b8df767a38517e705ae1f45' 
  AND token = 'gzVmgAD2CJKce7OqQALs01FDyQrB9L6Kp5lM1A9ilOw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}