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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c3f607d84ed2119a8c4de4c2abe04b9b6c63f2631b94f12406653effd65518ac' 
  AND token = 'nTAHmmT5vvrxTxKyHTMgcLKu3XS1Dz3NC8mEBLQuO1s=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}