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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2b896e3a257fbf5b88746ee9bb82416698f0d6426b2e820578a388c7758c53e6' 
  AND token = 'JMi5bvD1uPnsMBFVZuLqVwAbinQSURgN3tv1P3nm3DY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}