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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '18ba5b7caf8feb3aa7911a6631233bc0a168769ca0e2b58904c02c42cec6d70a' 
  AND token = 'GIVK9s8Q9DKqVQXOYW7+5U6IFCrs4thdkD9VldOKmEA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00029

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}