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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '9b5a721609254972de3570047724815f232ca6dee7d9c5f01d41c19e852cd2b6' 
  AND token = 'xOU3qMGMzvu+e/w/2Tyg+F5B+eoH7Qlu9EezjMYnARo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}