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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '468d38e3ebc84d9fe851f9e3ed33d66b002e5a00dd43413a0a4f676037df2241' 
  AND token = 'uZF9pquWK6nIOMYtyxGIjG1zNWQXnUE2j8g9l0Vgs+4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}