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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '81c9e8e4f6e9dcfd213f9fd0d16264295892e0ae10d590757fa58d3d57d27157' 
  AND token = 'ajbZ0/SM37qw7V7Wwt/QqgotUakmfwaVU1p1XzFRu/c=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00042

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}