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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd78c3d91d27e2af2086eea3090045f1bc92b02ef0ea9dab3c6080d4941298226' 
  AND token = '0u72bW2sAZKhx+szESFensCC3ohB+5ZXnW3CN6mOpP0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}