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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3e9aca59181d3ef49c8d54174687c7ffb63ff1f7f0f6935266d9f9709e9f40db' 
  AND token = 'EhsnRXR5e4fUvZNL2tmo/5U5QKaFVfTQud/QdChstpk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}