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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '004280c34b48c55d39253572d3fbb32a78e8ca359719c4ecf9274be9e5fb17c4' 
  AND token = '6+kpnkPafHEAbPe5LIQBHW3dwfG7yuXScZ7c0EBbtTk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}