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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '9f3b08516354e5a0c1838c9eb5ffe4ff05a13af6e52401230f15d3c8fc3ebead' 
  AND token = '+oNCgdjccR1oPDMUtIhqokwwoNnGf28VIMMaAgt81E4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}