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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0f1b5b34e4e560dbb446ccc114a648e2b5b788135c4dd699e150a0c0e7b33d54' 
  AND token = 'iclUmWCGNSqadwp+EDJD9ZtaSiVZIHuvuvpkUVCi2Ng=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00029

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}