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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '484e68f4d0ca4774493feb8ce142492f22f00cbcee2c31b8b2ec090c5338d1e1' 
  AND token = 'It41H9uY6hABe9HZNFgUsZQK98R9glgmGTHq8ciT1yY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}