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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6c2268396c5fc4f2e1725f2b699dcd034d64f3b999a60d6a97bcfaf5ac6b4070' 
  AND token = 'fyqXBSZsCSHxI2OAxZT2RapF+LdxHZCb1nJt5Sk9CeU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}