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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd749319bd26bcef410552149d81a7638e369fc5709368835c573b6e2102cba7b' 
  AND token = 'RhuA4d2NudfqiiYGbN6EvCAGVHNQEAFp2teHAWGahB8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}