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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '823f297f65c2b4c164eafb6db47a5fab453f045e126a28ba2b5a3ec7f26b7545' 
  AND token = 'mwZSw+iNstvWfQ7kZpQf1U9uvoY56+HHdGudfFvtr/k=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}