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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '50c791df5af360baf7f1172f0bf4e5ebe16e5621b3c9127d931d7a1639410521' 
  AND token = 'vyuh4CTj6MenqZWaO1fQm2pJ74uDWRBKhi0qgj57578=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00031

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}