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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '922f20ec40755723a5c5c810ab43bf965ad92073fb3419b10e6c4a01a6d10d40' 
  AND token = 'AfhX8cy2WKzq49Z3DLNGBserwMrJUxjarWL4SgOOwFk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}