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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '54396303192628c3777c85375a3cf652f60b054113c59855f3f96d47dde69a42' 
  AND token = '6bc7jaJh8vzM0EzMeGvPz+6k1zo1SJH42yXVcyR1cO8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}