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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4449ebe51060ac6577e102a92576a56095d1f0b543970eefc565b78fe1a895cb' 
  AND token = '9TBF0cPM+xlfcQ7Iz+HnVwhjCpk3lNAY1PA4QaDaDPg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}