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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a99612de2d4521c502468adcc19344f61880949f5787a989fe980d3e51e7ce73' 
  AND token = 'dWXs4zXItWcR6vAF8gGTe2g3h1xRvJ3H7AXoTpsBIPo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}