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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f87a282ddc1265917770128e974a706c07245f7d33a1b0c17813275f0f3538fa' 
  AND token = 'v1zNq7WHL4I7UGYwRENS6VA3ieHIJQnrffi2CKVJw+o=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}