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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '682622a2a091deef3b1b831a646c93d46d1eb19395cfbee1b693f8e8a9c2b942' 
  AND token = 'HfyTwV5F178Hjpf8b+7bgqeTkyI/1SobEiN5hqzz7aQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}