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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2226862085feb2791a0aecca37c19e9b7b51db3b07270be02f593196f3e13694' 
  AND token = 'FNmLQu2MERj2d9Yc8+DouDBPs+5zrnv3m9NIO/cN+2I=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}