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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4a6e8167a0a6530a700280de152aa522307ef53bf99645e48a34a066d7d7cea3' 
  AND token = 'rBj1iE6ZAvp4S4wqiu7PbonYe1WZpwJxnLe33PTCRso=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}